Welcome to the research lab of Ethan Chen, Assistant Professor of biology at Texas Tech University. We study how the interactions between tumor cells and immune niche, the alterations in tumor metabolic pathways and impacts of tumor stem cells contribute to the progression and development of tumors.
We use state-of-the-art approaches to address important questions in tumor biology, and a major goal of our research is to generate basic knowledge that would advance our understanding of cancer and a long term goal is to develop potential therapeutics that would impact the community by improving responses to therapy and by reducing the mortality rate in cancers.
Oct 27 2022
Our paper "Tumor Cell-Derived Asymmetric Dimethylarginine Regulates Macrophage Functions and Polarization." is accepted by Cancer Cell International. (Impact factor: 6.439) Link to the paper
Sep 1 2022
We move to Texas Tech University. More research fun !!
Aug 28 2022
Our editorial article "Splice modulating oligomers as cancer therapeutics" is now published on Genes & Cancer. Link to the article
Apr 13 2022
Zaida Laventure (master student in the lab) received admission to PhD program at Case Western Reserve University. Congratulations, Zaida!!
Apr 8-13 2022
We presented poster entitled "Tumor stem cell derived asymmetric dimethylarginine drives immune evasion via functional modulation of macrophages" at the American Association for Cancer Research 2022 in New Orleans. Link to the abstract
Nov 12-14 2021
The graduate student, Zaida Laventure, will attend the Annual Biomedical Research Conference for Minority Students (ABRCMS) and present a poster with the topic of Arginine metabolism and tumor immune evasion.
Aug 7 2021
The ""Prolactin enhances T Regulatory Cell Promotion of Breast Cancer through the Long Form Prolactin Receptor" was now available online as eprint
Aug 6 2021
The graduate student poster "Modulation of Macrophage Plasticity and polarization by Cancer Stem Cells" was selected as the top 20% abstract
Aug 4-6 2021
We are attending and presenting at Mississippi Academy of Sciences (Symposium)
Aug 3 2021
Our research work about tumor Tregs entitled "Prolactin enhances T Regulatory Cell Promotion of Breast Cancer through the Long Form Prolactin Receptor" was accepted by Translational Oncology today
June 21 2021
The "Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus" is published
May 27 2021
The "Sex differences in the immune system become evident in the perinatal period in the four core genotypes mouse" is published
May 26 2021
Our research work entitled "Visceral adipose tissue imparts peripheral macrophage influx into the hypothalamus" is accepted by Journal of Neuroinflammation
May 7 2021
Our research work entitled "Sex differences in the immune system become evident in the perinatal period in the four core genotypes mouse" is accepted by Frontiers in Endocrinology
Dec 2 2020
Our research work entitled "Sex Differences in Macrophage Responses to Obesity-Mediated Changes Determine Migratory and Inflammatory Traits" was accepted and published in Journal of Immunology.
Oct 7 2020
Dr. Ethan Chen received a 3-year NIH INBRE Developmental grant (2020-2023)
Aug 14 2020
Dr. Ethan Chen joined Delta State University